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Analysis suggests at least 14 days of antibiotic therapy for infants with E. coli bacteremia, indicating longer duration may be beneficial.
While the optimal duration of therapy for infants with E coli bacteremia without CSF evaluation requires further evaluation, our data suggest that infants should receive antibiotic therapy for at least 14 days and that longer durations (21 days) can be considered.
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Stark et al. (2026) studied this question.
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