Anthracene-based Molecular Rotor as a Theranostic Agent for Viscosity Sensing and Imaging-Guided Photodynamic Therapy

Ailada Jantasin; Supranee Watpathomsub; Thitima Pewklang; Tunyawat Khrootkaew; Sirimongkon Aryamueang; Bongkot Uengwanarat; Kantapat Chansaenpak; Mongkol Sukwattanasinitt; Anyanee Kamkaew

doi:10.1039/d5tb02822a

January 1, 2026Journal of Materials Chemistry B

Anthracene-based Molecular Rotor as a Theranostic Agent for Viscosity Sensing and Imaging-Guided Photodynamic Therapy

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Key Points

The aim is to develop a molecular probe that detects viscosity changes and serves therapeutic functions in cancer treatment.
Designed an anthracene-based molecular rotor.
Tested viscosity sensing capacity in cellular microenvironments.
Evaluated potential for imaging-guided photodynamic therapy.
The molecular probe demonstrated sensitivity to viscosity changes.
Effective imaging and therapeutic action were noted in cancer models.

Implication

Developing a molecular probe that senses viscosity and delivers therapy in cancer, indicating promise for treatment.

Abstract

Viscosity variations within cellular microenvironments are closely associated with pathological states such as cancer, motivating the development of molecular probes that integrate environmental sensing with therapeutic function. Here, we report...

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Cite This Study

Jantasin et al. (2026) studied this question.

synapsesocial.com/papers/699011812ccff479cfe5840f https://doi.org/10.1039/d5tb02822a

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Anthracene-based Molecular Rotor as a Theranostic Agent for Viscosity Sensing and Imaging-Guided Photodynamic Therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

Anthracene-based Molecular Rotor as a Theranostic Agent for Viscosity Sensing and Imaging-Guided Photodynamic Therapy

Key Points

Implication

Abstract

Discussion

Cite This Study

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