What question did this study set out to answer?

The aim is to develop a molecular probe that detects viscosity changes and serves therapeutic functions in cancer treatment.

February 14, 2026Journal of Materials Chemistry B1 citations

Anthracene-based Molecular Rotor as a Theranostic Agent for Viscosity Sensing and Imaging-Guided Photodynamic Therapy

AJAilada JantasinSuranaree University of Technology SWSupranee WatpathomsubBangkokthonburi University TPThitima PewklangSuranaree University of Technology

Key Points

The aim is to develop a molecular probe that detects viscosity changes and serves therapeutic functions in cancer treatment.
Designed an anthracene-based molecular rotor.
Tested viscosity sensing capacity in cellular microenvironments.
Evaluated potential for imaging-guided photodynamic therapy.
The molecular probe demonstrated sensitivity to viscosity changes.
Effective imaging and therapeutic action were noted in cancer models.

Abstract

Viscosity variations within cellular microenvironments are closely associated with pathological states such as cancer, motivating the development of molecular probes that integrate environmental sensing with therapeutic function. Here, we report...

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