Natural compound arctigenin facilitates mucosal healing in ulcerative colitis by promoting focal adhesion disassembly in colon cells, indicating potential therapeutic benefits.
Arctigenin enhances the autophagic degradation of paxillin by reducing excitatory amino acid transport to promote focal adhesion disassembly in colonic epithelial cells, thereby facilitating mucosal healing in the context of ulcerative colitis.
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Zhao et al. (2026) studied this question.
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