January 1, 2011Open Access

Smoking and Smoking Cessation in Relation to All-Cause Mortality and Cardiovascular Events in 25,464 Healthy Male Japanese Workers

PICO estructurado

Does smoking cessation reduce total CVD events and all-cause mortality in healthy male Japanese workers?

Población

Healthy young- and middle-aged male Japanese workers

Intervención

Smoking (11-20 cigarettes/day) and smoking cessation (quitting for ≥ 4 years)

Comparador

Non-smokers and continued smokers

Resultado

Total cardiovascular (CVD) events and all-cause mortalityhard clinical

Smoking cessation for at least 4 years significantly reduces the risk of cardiovascular events and all-cause mortality in healthy young and middle-aged men.

Resumen

In healthy young- and middle-aged Japanese males, a significant increase in HR for total CVD events was confirmed for a smoking level of 11-20 cigarettes/day. Quitting reduced the HR for total CVD events, with quitting for ≥ 4 years being statistically significant. A similar trend was observed for all-cause mortality.

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