A systematic study on the competitive oxidation of glucose (Glc), xylose (Xyl), and 5-hydroxymethylfurfural (HMF) vs the oxygen evolution reaction (OER) was performed by coupling H-cell electrochemical experiments with in situ O 2 monitoring in the anodic chamber using an activated Ni foam as the anode. At a substrate concentration of 10 mM, multipotential steps showed similar OER onset potential values for Glc and Xyl (1.49 V RHE ), while the value for HMF was slightly lower (1.47 V RHE ). Chronoamperometry tests at 1.6 V RHE (30 min) with varying concentrations showed that both Glc and Xyl oxidation reactions fully suppressed the OER at 30 mM, while 100 mM was required for HMF. A Langmuir–Hinshelwood analysis of the current–substrate concentration dependence revealed the slower kinetics and inhibitory effects impacting HMF oxidation, which account for the significant difference in performance with respect to both aldoses. Given its relevance as both a model and a promising substrate for membraneless electrolysis operation, Glc was further investigated in a long-term chronoamperometry experiment with in situ O 2 monitoring (15 h at 1.6 V RHE , 30 mM Glc). The results suggested the feasibility of sustaining OER-free operational conditions for approximately 4 h from an initial Glc concentration of 100 mM. HPLC analysis indicated the presence of formate as the main coproduct of hydrogen via glucose electrolysis. This publication is licensed under You are free to share (copy and redistribute) this article in any medium or format and to adapt (remix, transform, and build upon) the material for any purpose, even commercially within the parameters below: Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. *Disclaimer This summary highlights only some of the key features and terms of the actual license. It is not a license and has no legal value. Carefully review the actual license before using these materials. You are free to share (copy and redistribute) this article in any medium or format and to adapt (remix, transform, and build upon) the material for any purpose, even commercially within the parameters below: Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. *Disclaimer This summary highlights only some of the key features and terms of the actual license. It is not a license and has no legal value. Carefully review the actual license before using these materials. You are free to share (copy and redistribute) this article in any medium or format and to adapt (remix, transform, and build upon) the material for any purpose, even commercially within the parameters below: Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. *Disclaimer This summary highlights only some of the key features and terms of the actual license. It is not a license and has no legal value. Carefully review the actual license before using these materials.
Crisafulli et al. (Mon,) studied this question.
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