PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 19, 2026Organic Letters2 citations

Controlled Helical Distortion of Double Thia7helicenes via Inner-Rim Alkyl Substitution

View Full Paper
DWDehe WangJTJingyun TanLZLong Zhou

Key Points

  • The aim is to manipulate helical distortion in double thia[7]helicenes using inner-rim alkyl substitutions.
  • Conducted structural and computational studies
  • Applied inner-rim alkyl substitution to double thia[7]helicene
  • Analyzed changes in optical, electronic, and chiroptical properties
  • Increased backbone distortion observed in substituted helicenes
  • Enhanced through-space interactions noted
  • Significant changes in optical and chiroptical properties reported
  • Improved efficiency in singlet oxygen photosensitization found

Abstract

Precise control of helical distortion in double helicenes is challenging due to their high intrinsic strain. Herein, we report modulation of helical distortion in a double thia7helicene through inner-rim alkyl substitution. Structural and computational studies reveal increased backbone distortion and enhanced intramolecular through-space interactions. These subtle structural variations lead to notable changes in optical, electronic, and chiroptical properties and enable efficient singlet oxygen photosensitization.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Wang et al. (2026) studied this question.

synapsesocial.com/papers/6996a7b5ecb39a600b3ed9a7https://doi.org/10.1021/acs.orglett.6c00027
Ask AI
Helpful
Bookmark
Share
View Full Paper