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Synapse
February 19, 2026Development0 citationsOpen Access

The people behind the papers – Veronica Castle, Rodrigo Fernandez-Gonzalez and Gonca Erdemci-Tandogan

Key Points

  • To investigate the effects of cell divisions on the tissue boundary between ectoderm and mesectoderm in Drosophila embryos.
  • Combined computational modelling with in vivo experimental techniques
  • Focused on the boundary dynamics between ectoderm and mesectoderm
  • Analyzed mechanical forces involved during cell division
  • Identified critical role of cell division in maintaining tissue boundaries
  • Demonstrated how disruptions can affect normal development

Abstract

Boundaries between tissues are important for establishing correct patterning during development and must be able to resist forces generated in the tissue from processes such as cell division. In a new study, Veronica Castle, Rodrigo Fernandez-Gonzalez, Gonca Erdemci-Tandogan and colleagues combine computational modelling with in vivo experiments to investigate how cell divisions impact the boundary between the ectoderm and mesectoderm tissue in the Drosophila embryo. To find out more, we spoke to first author Veronica Castle and co-corresponding authors Rodrigo Fernandez-Gonzalez, Professor at the University of Toronto, Canada, and Gonca Erdmeci-Tandogan, Assistant Professor at the University of Western Ontario, Canada.

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Cite This Study

A 2026 study studied this question.

synapsesocial.com/papers/6996a7c3ecb39a600b3edb9chttps://doi.org/10.1242/dev.205546
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