Demonstrates a method to synthesize tri- and tetrasubstituted olefins, highlighting its broad applicability and precision.
A general cobalt‐catalyzed oxidative cyclization strategy for the stereoselective synthesis of tri‐ and tetrasubstituted alkenes from readily available 1,3‐enynes is presented. This method employs an earth‐abundant cobalt catalyst and exhibits broad functional group tolerance, delivering the multisubstituted olefins with high regioselectivity and excellent Z / E control.
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Tan et al. (2026) studied this question.
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