ABSTRACT Background Self‐inflicted skin injury is a significant yet often underrecognized contributor to acne progression, particularly in postadolescent populations. It not only perpetuates lesions but also triggers inflammatory cascades, including sebaceous gland epithelialization and cystic transformation. Postadolescent acne excoriée poses unique therapeutic challenges due to the interplay of dermatological and psychological factors. Aims To evaluate the effectiveness of a combined psychodermatological treatment—CO 2 laser ablation and cognitive–behavioral therapy (CBT)—in managing chronic, treatment‐resistant postadolescent acne excoriée. Methods A case series of three patients with refractory postadolescent acne excoriée was conducted. Treatment involved CO 2 laser ablation to remove obstructed sebaceous glands, combined with CBT targeting maladaptive excoriation behaviors. Results All patients achieved rapid and sustained clinical improvement. The combined approach disrupted the pathomimetic cycle, eliminated visible obstructed sebaceous glands, and reduced compulsive skin manipulation. Conclusion Integrating CO 2 laser ablation with CBT offers a dual benefit of addressing both the physical lesions and psychological drivers of acne excoriée. Multidisciplinary collaboration is essential for effective management of complex psychocutaneous disorders.
Penev et al. (Sun,) studied this question.