Comparative analysis of four sequencing platforms for methylation sequencing

This study conducts a comprehensive assessment of four sequencing platforms: GenoLab M (Genemind), NovaSeq X (Illumina), T7 (MGI) and Salus Pro (Salus), focusing on different performance metrics related to methylation data. By analyzing data from plasma cfDNA samples, we assessed key metrics including sequencing quality, CpG coverage, data efficiency, and methylation level consistency. These findings aim to provide valuable insights into the consistency of sequencing platforms for researchers and laboratories when integrating multiple methylation datasets for analysis.