A case highlights EBV lymphoma in a patient on tofacitinib and methotrexate, suggesting careful diagnosis and monitoring.
EBV-associated primary vitreoretinal lymphoma may arise in the context of combined methotrexate and JAK inhibitor therapy. This case highlights the importance of considering masquerade syndromes in steroid-refractory uveitis, incorporating EBV PCR testing into diagnostic workup, and recognizing the potential role of immunosuppression in ocular lymphomagenesis.
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Qin et al. (2026) studied this question.
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