Sensitive and rapid DPV detection of urinary homovanillic acid via g-C ₃ N ₄ @nZVI modified carbon paste sensor

Aya A. Mouhamed; Maria Osama Mekhail; Taher Taha Zaki; Amr M. Mahmoud; Aya T. Soudi

doi:10.1039/d5ra08154h

January 1, 2026RSC AdvancesOpen Access

Sensitive and rapid DPV detection of urinary homovanillic acid via g-C ₃ N ₄ @nZVI modified carbon paste sensor

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Key Points

The study aims to develop a sensitive method for detecting homovanillic acid in urine, a biomarker for neuroblastoma.
Utilized a g-C3N4@nZVI modified carbon paste sensor for detection,
Employed differential pulse voltammetry for analysis of samples.
Focused on achieving non-invasive urinary testing for accuracy.
Demonstrated high sensitivity in detecting homovanillic acid levels,
Successfully quantified HVA in complex biological fluids,
Indicated potential applications in identifying neuroblastoma and related cancers.

Implication

This research demonstrates rapid detection of homovanillic acid in urine, indicating its potential for cancer diagnosis.

Abstract

Non-invasive and rapid detection of HVA, a validated urinary biomarker for neuroblastoma and catecholamine-secreting cancers, demands highly sensitive analytical approaches capable of reliable quantification in complex biological fluids.

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Cite This Study

Mouhamed et al. (2026) studied this question.

synapsesocial.com/papers/6996a869ecb39a600b3ef0c2 https://doi.org/10.1039/d5ra08154h

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Sensitive and rapid DPV detection of urinary homovanillic acid via g-C ₃ N ₄ @nZVI modified carbon paste sensor

Key Points

Implication

Abstract

Discussion

Cite This Study

Sensitive and rapid DPV detection of urinary homovanillic acid via g-C ₃ N ₄ @nZVI modified carbon paste sensor

Key Points

Implication

Abstract

Discussion

Cite This Study

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