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February 19, 2026RSC Advances6 citationsOpen Access

Sensitive and rapid DPV detection of urinary homovanillic acid via g-C 3 N 4 @nZVI modified carbon paste sensor

AMAya A. MouhamedMMMaria Osama MekhailTZTaher Taha Zaki

Key Points

  • The study aims to develop a sensitive method for detecting homovanillic acid in urine, a biomarker for neuroblastoma.
  • Utilized a g-C3N4@nZVI modified carbon paste sensor for detection,
  • Employed differential pulse voltammetry for analysis of samples.
  • Focused on achieving non-invasive urinary testing for accuracy.
  • Demonstrated high sensitivity in detecting homovanillic acid levels,
  • Successfully quantified HVA in complex biological fluids,
  • Indicated potential applications in identifying neuroblastoma and related cancers.

Abstract

Non-invasive and rapid detection of HVA, a validated urinary biomarker for neuroblastoma and catecholamine-secreting cancers, demands highly sensitive analytical approaches capable of reliable quantification in complex biological fluids.

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Cite This Study

Mouhamed et al. (2026) studied this question.

synapsesocial.com/papers/6996a869ecb39a600b3ef0c2https://doi.org/10.1039/d5ra08154h
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