Introduction: The durability of silicone breast implants is critical for successful aesthetic and reconstructive outcomes. Intraoperative breast pocket irrigation is routinely performed to reduce infection and capsular contracture, but the effect of commonly used irrigants on implant shell integrity remains unclear. Methods: Silicone breast implant shells from Mentor and Allergan Natrelle were sectioned into 2.5 × 2.5 cm samples and randomly allocated to 5 irrigant groups: 0.9% normal saline, triple antibiotic solution (clindamycin, cefazolin, gentamicin), 0.05% chlorhexidine gluconate (Irrisept ® ), 10% povidone-iodine (Betadine ® ), and Poloxamer 188 (SAF-Clens ® AF). Each sample was immersed in its respective irrigant for 60 s then tested for tensile strength using a commercial tensiometer with a 1.0 cm displacement. Data were analyzed using one-way ANOVA with Tukey's HSD post hoc testing. Results: Average preimmersion tensile strength was 8.58 N. Postimmersion tensile strengths were 8.25 N (saline), 8.94 (triple antibiotic), 8.84 N (chlorhexidine gluconate), 8.08 N (povidone-iodine), and 7.41 N (Poloxamer 188). No statistically significant differences were found among groups (ANOVA, P = .085), though a trend toward reduced tensile strength following Poloxamer exposure was observed. Conclusions: Normal saline, triple antibiotic solution, chlorhexidine gluconate, and povidone-iodine did not significantly affect the tensile strength of silicone breast implant shells. Poloxamer 188, however, showed a trend toward greater reduction in tensile strength and should be thoroughly rinsed prior to implant placement. These findings support the safe use of conventional antiseptic and antibiotic irrigants with minimal impact on implant mechanical integrity.
Thomas et al. (Tue,) studied this question.