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Prototype MRI phantom replicates realistic anatomy and contrast, improving accessibility for scientists and clinicians.
Purpose To empower MR scientists and clinicians to produce customized, high‐definition anthropomorphic MRI phantoms directly from patient or volunteer DICOM images using commercially available 3D printers and printing materials. Methods Suitable 3D printing materials were identified and calibrated to reproduce target MR image contrasts when scanned using clinical MR sequences with default acquisition parameters. A custom software tool was developed to convert the DICOM images into 3D‐printing material maps, in which micrometer‐scale droplets of three distinct printing materials were spatially intermixed to replicate tissue‐equivalent contrasts consistent with those in the source MR images. Results A prototype MR head phantom was fabricated based on 0.5 × 0.5 × 1.0 mm 3 resolution head images acquired from a volunteer. When scanned with clinical MR sequences across various contrast settings, the phantom images reproduced fine anatomical details, demonstrating the phantom's ability to replicate realistic anatomy. Conclusion This work advances the efforts to bridge the gap between the needs of researchers and clinicians for MRI phantoms with realistic anatomy and tissue‐specific contrast, and the practical availability of such phantoms to all interested users. The approach eliminates the need for complex image segmentation, advanced computer‐aided design (CAD) skills, specialized manufacturing techniques, or in‐depth knowledge of material science.
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Popescu et al. (2026) studied this question.
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