Why the study?
Does congenital heart disease increase the risk of maternal cardiac events and complications during pregnancy compared to women without CHD?
Case-Control (n=483)
No
Does congenital heart disease increase the risk of maternal cardiac events and complications during pregnancy compared to women without CHD?
Pregnant women with congenital heart disease face a 2.5-fold higher risk of maternal cardiac events and doubled length of hospital stay, underscoring the need for standardized cardio-obstetric triage and delivery planning.
Survivorship among individuals with CHD has expanded, bringing more pregnancies into routine care. In this issue, a single-centre retrospective case–control study (162 CHD deliveries vs 321 controls) reports higher composite maternal cardiac events (8.6 vs 3.4%; risk ratio 2.5, 95% CI 1.2–5.4), greater use of operative or assisted delivery, and an approximately doubled length of stay. Modified WHO class correlates with length of stay but not with discrete cardiac events; maternal age independently predicts cardiac events; rates of pre-eclampsia are lower in CHD. These findings support first-trimester cardio-obstetric triage, standardised delivery bundles, and capacity planning that uses risk class to anticipate monitoring needs, with routine 6–12-week postpartum review. Limitations include selection, era differences, and modest sample size. Overall, anticipatory planning and disciplined intrapartum decision-making remain key to safe, resource-aware care for pregnant women with CHD.
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Pesce et al. (2026) conducted a case-control in Pregnant women with congenital heart disease (CHD) undergoing delivery compared to matched controls without CHD (n=483). CHD management during pregnancy vs. Pregnant women without CHD was evaluated on Composite maternal cardiac events during pregnancy and delivery (Risk ratio 2.5, 95% CI 1.2-5.4).
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