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February 20, 2026BMJ OpenOpen Access

Feasibility and efficacy of virtual reality rehabilitation for upper extremity impairment in ischaemic stroke patients: an open-label, parallel-group, randomised controlled trial

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Authors

PSPadmavathy Narayanapillai SylajaSPSrijithesh PRRPRinta Paul

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Overview

An open-label trial evaluates VR intervention for upper extremity recovery in stroke patients, suggesting feasibility but no superiority over physiotherapy.

Key Points

  • The research aimed to evaluate the feasibility and efficacy of a non-immersive virtual reality system for upper extremity recovery in ischaemic stroke patients.
  • Conducted an open-label, parallel-group, randomised controlled trial
  • Assigned participants to VR intervention or conventional physiotherapy
  • Included 60 first-ever ischaemic stroke patients within 1-6 months of stroke onset
  • Compared a 12-week VR rehabilitation program with conventional physiotherapy
  • Assessed outcomes such as motor function, activities of daily living, and quality of life using various assessments.
  • No significant differences in treatment compliance between groups (p=0.19)
  • Both groups showed improvements in motor performance and quality of life
  • No significant differences in the Fugl-Meyer assessment (p=0.58) and other outcome measures
  • The findings suggest VR was feasible and safe but not superior to physiotherapy.

Cite This Study

Sylaja et al. (2026) studied this question.

synapsesocial.com/papers/6997fa12ad1d9b11b345304fhttps://doi.org/10.1136/bmjopen-2025-107014
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