Development of a transcription factor-based biosensor strain for reporting α-terpineol production via the alcohol-dependent hemiterpene pathway in Escherichia coli

Catherine A Odhiambo; Isaac Ali; Gavin Williams

doi:10.1039/d5cb00310e

January 1, 2025RSC Chemical BiologyOpen Access

Development of a transcription factor-based biosensor strain for reporting α-terpineol production via the alcohol-dependent hemiterpene pathway in Escherichia coli

View Full Paper

Ask AI

Bookmark

Share

Key Points

The research aims to create a biosensor strain that effectively reports α-terpineol production through engineered pathways in E. coli.
Design and construction of a biosensor using transcription factors.
Cultivation of engineered E. coli strains.
Assessment of α-terpineol production levels.
The engineered biosensor successfully detected variations in α-terpineol production.
Quantitative measurements indicated improved production rates compared to previous methods.

Implication

This investigation develops a biosensor to measure α-terpineol production in E. coli, indicating new methods for terpenoid synthesis.

Abstract

Terpenes constitute a vast and industrially important class of natural products. Yet, microbial production of many high-value terpenoids remains limited by the difficulty of rationally engineering their biosynthetic pathways and...

Discussion

No takes yet. Share an insight, caveat, or question.

Cite This Study

Odhiambo et al. (2025) studied this question.

synapsesocial.com/papers/6997fa6dad1d9b11b34539c2 https://doi.org/10.1039/d5cb00310e

View Full Paper

Ask AI

Bookmark

Share

Development of a transcription factor-based biosensor strain for reporting α-terpineol production via the alcohol-dependent hemiterpene pathway in Escherichia coli

Key Points

Implication

Abstract

Discussion

Cite This Study

Development of a transcription factor-based biosensor strain for reporting α-terpineol production via the alcohol-dependent hemiterpene pathway in Escherichia coli

Key Points

Implication

Abstract

Discussion

Cite This Study

Keep reading

Keep reading