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February 21, 2026ACS Nano

In Situ Dynamic Polymerization Spinning of All-Hydrogel Optrode with Stable Syncretic Interface for Long-Term Tolerance of Tissue Micromotion

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Authors

HPHongyu PanDonghua UniversityJZJiahao ZhengKunming University of Science and TechnologySXSiming XuFudan University

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Implication

In situ dynamic polymerization spinning shows stable biocompatibility in hydrogel optrode, indicating long-term performance against tissue micromotion.

Key Points

  • This research aims to enhance the stability and performance of hydrogel optrodes under tissue micromotion.
  • Fabrication of an all-hydrogel optrode using in situ dynamic polymerization spinning.
  • Development of a semiopen ceramic ferrule to reduce moisture loss.
  • Assessment of mechanical compliance and interfacial toughness in the hydrogel optrode.
  • The hydrogel optrode exhibits exceptional interfacial toughness of 16.28 J/m².
  • Light-guiding property recorded at 0.523 dB/cm at a wavelength of 473 nm.
  • Demonstrated minimal inflammatory response and stable performance under physiological conditions.

Cite This Study

Pan et al. (2026) studied this question.

synapsesocial.com/papers/69990de85b97ab4c14ac27c0https://doi.org/10.1021/acsnano.5c19710
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