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February 21, 2026Biophysical Journal0 citations

BPS2026 - Integrating quantum sensing and acoustic force for drug development and ribosome research

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SXShoujun XuYWYuhong Wang

Key Points

  • The central aim is to develop a new technique that combines quantum sensing with acoustic force for advanced drug development and ribosome research.
  • Integrated acoustic force with atomic magnetometry.
  • Developed super-resolution force spectroscopy (SURFS).
  • Achieved unprecedented measurement resolution of intermolecular bonds.
  • SURFS resolves intermolecular bonds with 0.3 pN resolution.
  • The technique offers a larger field-of-view than traditional methods.

Abstract

Quantum sensing uses spin coherence to probe physical parameters with exceptional precision and capability. One of the main tools in this field is atomic magnetometry, which relies on optically pumped atomic alignment to directly measure magnetic fields with the highest sensitivity to date. By integrating acoustic force with an atomic magnetometer, we have invented super-resolution force spectroscopy (SURFS) that resolves intermolecular bonds with an unprecedented 0.3 pN resolution. The new technique has a much larger field-of-view than the usual single-molecule force techniques and has

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Cite This Study

Xu et al. (2026) studied this question.

synapsesocial.com/papers/69990df65b97ab4c14ac2c66https://doi.org/10.1016/j.bpj.2025.11.1466
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