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February 21, 2026Global Pediatrics0 citationsOpen Access

Plummer–Vinson Syndrome Presenting with Dysphagia in a Pediatric Patient: A rare Case Report and Review of Management

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MAMohamed Issak AdanInstitute of Child HealthYSYahye A. Mohamud SholeUniversity of SomaliaAMAbdikarin Ahmed Mohamed

Key Points

  • This report aims to present a rare case of Plummer-Vinson syndrome in a pediatric patient and discuss management strategies.
  • Case report of an eight-year-old girl with dysphagia and anemia.
  • Laboratory studies to confirm microcytic hypochromic anemia.
  • Upper GI series to identify the presence of an esophageal web.
  • Initial treatment with oral iron followed by esophagogastroduodenoscopy.
  • Confirmed diagnosis of Plummer-Vinson syndrome through endoscopic findings.
  • Esophagogastroduodenoscopy revealed a web at the upper esophageal sphincter.
  • Successful endoscopic dilation led to resolution of dysphagia symptoms.

Abstract

Plummer-Vinson syndrome (PVS), also known as Paterson-Brown-Kelly syndrome, is a rare disorder marked by iron deficiency anemia, difficulty swallowing, and upper esophageal webs. It predominantly affects middle-aged women and is rarely observed in children. Although the precise mechanisms remain unclear, iron deficiency is frequently implicated as the underlying cause. This report details an unusual pediatric case of PVS in an eight year-old girl with longstanding anemia and progressive dysphagia. Laboratory studies confirmed microcytic hypochromic anemia, and an upper GI Series suggested a proximal esophageal web. Initial treatment with oral iron showed no improvement. Eventually, an esophagogastroduodenoscopy confirmed the presence of a web near the upper esophageal sphincter. Endoscopic dilation was performed successfully, allowing for resolution of symptoms.

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Cite This Study

Adan et al. (2026) studied this question.

synapsesocial.com/papers/69994a7f873532290d01eea8https://doi.org/10.1016/j.gpeds.2026.100326
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