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February 21, 2026Journal of Clinical Tuberculosis and Other Mycobacterial Diseases0 citationsOpen Access

Clinical Presentation and Outcomes of Children Hospitalized with Sickle Cell Anemia

Clinical presentation and outcomes of children hospitalized with sickle cell anemia at Gulu Regional Referral Hospital, Uganda: A retrospective cross-sectional study

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Authors

KOKeneth OkelloMOMorrish Obol OkelloFCFred Sual Chemutai

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Overview

Retrospective study evaluates clinical outcomes in hospitalized children with sickle cell anemia, suggesting improved recovery rates.

Key Points

  • Evaluate clinical presentations and health outcomes of children with sickle cell anemia hospitalized in Uganda.
  • Retrospective cross-sectional study design
  • Reviewed medical records of children aged 0–18 hospitalized with sickle cell anemia
  • Data collection on demographics, clinical presentations, interventions, and outcomes
  • Descriptive statistical analysis using Stata 18.0
  • Most common symptoms were painful crises (86.5%) and fever (66.7%)
  • High recovery rate of 94.4%, with short hospital stays (98.4% stayed less than one week)
  • Mortality rate was 3.9%, lower than rates reported in other African settings
  • Limited use of hydroxyurea (14.3%) highlighted barriers to treatment

Cite This Study

Okello et al. (2026) studied this question.

synapsesocial.com/papers/69994aab873532290d01f0aehttps://doi.org/10.1016/j.jctube.2026.100592
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