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February 21, 2026ACS Applied Nano Materials

An Electrochemical Sensor Using a Derivative of β-Cyclodextrin, Spherical Graphite, and Reduced Graphene Oxide for Sensing of Caffeic Acid

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Authors

YDYanhui DongSZS. Y. ZhangWPWen-Yuan Pei

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Overview

The study develops an electrochemical sensor to detect caffeic acid, indicating potential applications in food safety.

Key Points

  • This research aims to create an effective electrochemical sensor for detecting caffeic acid due to its health implications.
  • Synthesis of β-cyclodextrin derivative using 4-mercaptopyridine
  • Preparation of a ternary composite using β-cyclodextrin, spherical graphite, and reduced graphene oxide
  • Characterization of the composite structure using scanning electron microscopy
  • Evaluation of electrochemical detection performance on glassy carbon electrode for caffeic acid
  • Wide linear detection range for caffeic acid from 0.004 to 35 μM
  • Low limit of detection at 1.17 nM
  • High recovery rates of 97.59–100.30% in caffeic acid tablets and 97.26–100.21% in blueberries

Cite This Study

Dong et al. (2026) studied this question.

synapsesocial.com/papers/69994ba9873532290d01fd83https://doi.org/10.1021/acsanm.5c05873
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