Decoding the interplay between protic ionic liquids and drug: spectrophotometric, electrochemical, and DFT exploration of mitoxantrone

Key Points

• To analyze how protic ionic liquids interact with the drug mitoxantrone using various methods.
• Used spectrophotometric analysis to study light absorption changes in mitoxantrone.
• Employed electrochemical techniques to assess the interactions and stability of the drug.
• Applied Density Functional Theory (DFT) for theoretical insights into molecular interactions.
• Identified significant absorption changes in mitoxantrone when combined with protic ionic liquids.
• Electrochemical results indicate improved stability for the drug in the presence of these ionic liquids.
• DFT calculations suggest strong molecular interactions between mitoxantrone and protic ionic liquids.