Itching for relief: A review of the psychological impact of prurigo nodularis

Prurigo nodularis is a chronic, pruritic dermatological condition associated with a variety of symptoms, yet assessing and monitoring patients’ mental health is often overlooked. The impact of prurigo nodularis on mental health is readily apparent through several quality peer-reviewed studies. Prurigo nodularis is associated with an increased risk of anxiety, depression, and decreased quality of life. Many studies propose that pruritus is a primary factor in increasing mental health comorbidities in those affected by prurigo nodularis. Dermatology providers must screen for associated mental comorbidities of prurigo nodularis and refer patients for appropriate treatment as necessary. Utilizing reputable screening tools to assess and escalate medical care for patients improves quality of life. Biologic injectables have demonstrated an improvement in mental health comorbidities, therefore, implementation should be considered more readily when a patient presents with or develops signs of anxiety, depression, or decreased quality of life. Aggressive treatment of prurigo nodularis with a holistic approach improves quality of life.