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February 21, 2026Journal of Evidence-Based Integrative MedicineOpen Access

Effectiveness of Non-Pharmacological Interventions for Hormone Therapy-Induced Hand Arthralgia in Breast Cancer Patients: A Systematic Review

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Authors

NMNuria Muñoz-BermúdezVAVanessa Abril-EstebanAVAntonio Vitiello

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Overview

Systematic review evaluates non-pharmacological interventions for pain management in breast cancer survivors, suggesting promising findings.

Key Points

  • To evaluate the efficacy of non-pharmacological interventions for hormone therapy-induced arthralgia in breast cancer patients.
  • Systematic search of PubMed, Scopus, and Web of Science for RCTs from 2010 to 2025.
  • Independently performed study selection and data extraction by two reviewers.
  • Quality appraisal of studies using standardized criteria.
  • Eight RCTs met inclusion criteria, including interventions like acupuncture and structured exercise.
  • Acupuncture reduced pain intensity significantly, with mean differences of 0.9-1.1 points on the Brief Pain Inventory.
  • Exercise programs showed moderate improvements in pain, function, and quality of life.

Cite This Study

Muñoz-Bermúdez et al. (2026) studied this question.

synapsesocial.com/papers/69994cb3873532290d021631https://doi.org/10.1177/2515690x261423036
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