Testing reveals intrathecal antibody synthesis linked to stiff person syndrome and cerebellar ataxia.
Background: GAD65 antibodies (GAD65Abs) are implicated in autoimmune-mediated neurological syndromes, including stiff person syndrome and cerebellar ataxia. Identification of intrathecal GAD65Ab synthesis could provide relevant clinical information to requesting physicians.
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Tobin et al. (2026) studied this question.
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