Observations reveal reactivity and malignancy-like changes from tattoo pigment in lymph nodes, implying clinical significance.
Introduction: Tattoos are created by injecting pigments into the dermis. This causes an acute inflammatory reaction; pigments are actively and passively transported to regional lymph nodes which then display macro- and microscopic changes indicating reactivity and deposition of pigment. 1 Tattoo pigment in lymph nodes may cause clinical and radiological changes that mimic malignancy.
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Mulhare et al. (2026) studied this question.
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