Case report reveals culture-negative endocarditis in a child with congenital heart disease, indicating surgical intervention is crucial.
Kingella kingae , typically known for causing osteoarticular infections in young children, is an emerging cause of infective endocarditis (IE) in older children with congenital heart disease. This report describes a 12‐year‐old with repaired tetralogy of Fallot and a bioprosthetic pulmonary valve who developed culture‐negative IE due to K. kingae , confirmed by microbial cell‐free DNA testing and valve tissue PCR. His course was complicated by septic pulmonary emboli, requiring valve replacement. The case highlights the role of molecular diagnostics in managing culture‐negative IE and the need for timely surgical intervention in the presence of embolic complications.
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Jocson et al. (2026) studied this question.
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