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February 22, 2026Journal of Emerging Technologies and Innovative Research0 citations

Schiff base and their metal complexes: synthesis, characterization And Biological activity

MCM. B. Chougule

Key Points

  • The aim is to synthesize and characterize Schiff base metal complexes and evaluate their biological activity against several microorganisms.
  • Synthesis of metal complexes using Cu(II), Ni(II), Co(II), Mn(II), and Fe(III) ions with Schiff base ligands.
  • Characterization using techniques like elemental analysis, IR, NMR, UV-visible spectroscopy, and thermal analysis.
  • Conductivity measurements to determine electrolyte properties of the complexes.
  • Biological activity screening against fungi and bacteria such as Aspergillus niger and E. coli.
  • The synthesized metal complexes demonstrated thermal stability and were characterized as non-electrolytes in a 1:2 ratio.
  • Magnetic measurements suggested a distorted octahedral geometry of the complexes.
  • The complexes exhibited varying degrees of biological activity against tested microorganisms.

Abstract

Thermally stable complexes of, Cu(II), Ni(II), Co(II), Mn(II) and Fe(III) metal ions, Schiff bases (L1) (4-(1-(4-hydroxy-6-methyl-[(2-oxo-2H-pyran-3-yl) ethylideneamino) phenyl) acetamide. derived from P – amino acetanilide and the heterocyclic compound Dehydroacetic acid (DHA) and characterized by elemental analysis, IR, NMR,ultra violet visible spectroscopy, conductivity, thermal analysis, magnetic measurements, and a microbial study. The magnetic measurements and ultra violet visible spectral data of the complexes suggest a desorted octahedral geometry around the central metal ion. The molar conductance data revealed that all the complexes were non electrolytes in the ratio 1:2 (metal:ligand). The thermal stability of the complexes were studied by thermogravimetry. The ligands and their metal complexes were screened for biological activity against Aspergillusniger, Fusariumoxysporum, E. coli and Staphylococcus aureus.

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Cite This Study

M. B. Chougule (2026) studied this question.

synapsesocial.com/papers/699a9d7a482488d673cd3677https://doi.org/10.56975/jetir.v13i2.575342
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