A polyomavirus detected in American black bear (Ursus americanus)

Polyomaviruses are ancient DNA viruses that infect several species of animals. While recognition of the family Polyomaviridaehas grown rapidly, there are few studies that consider their potential association with disease. Carnivora are a diverseand widespread order affected by polyomaviruses (PyVs) that have co-evolved with their hosts for millions of years. PyVshave been identified in sea lions, raccoons, badgers, Weddell seals, and dogs. We have discovered a polyomavirus, tentativelynamed "Ursus americanus polyomavirus 1" (UaPyV1) in black bears (Ursus americanus). UaPyV1 was detectable in varioustissues of six out of seven bears submitted for necropsy. Based on viral phylogenetic clustering and detection of the virusin multiple individuals, we suggest that black bears are the natural hosts for UaPyV1. In this albeit small group, there is noclear relationship between UaPyV1 infection and any specific disease.