PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 23, 2026Circulation Reports0 citationsOpen Access

Refining the Cardiovascular–Kidney–Metabolic Staging System for Improved Risk Stratification of Chronic Kidney Disease Progression in Type 2 Diabetes

View Full Paper
TGTomohito GohdaNKNozomu KameiMTMarenao Tanaka

Key Points

  • The study aims to enhance the prognostic accuracy of the cardiovascular-kidney-metabolic staging system for chronic kidney disease progression in type 2 diabetes.
  • Refined the CKM staging system by incorporating risk categories based on eGFR and UACR.
  • Assessed the original CKM Stage 2 categorization.
  • Considered the impact of improved classification on prognostic accuracy.
  • Refinement of the CKM staging system resulted in improved risk stratification for CKD progression.
  • Incorporation of eGFR and UACR categories enhanced predictive capabilities.

Abstract

Background: The original cardiovascular–kidney–metabolic (CKM) staging system uniformly categorized all individuals with type 2 diabetes (T2D) as Stage 2. We aimed to improve the prognostic accuracy for chronic kidney disease (CKD) progression by incorporating the Kidney Disease: Improving Global Outcomes risk categories – based on estimated glomerular filtration rate (eGFR) and urinary albumin-to-creatinine ratio (UACR) – into CKM Stage 2.

Ask AI
Helpful
Bookmark
Share
View Full Paper

Cite This Study

Gohda et al. (2026) studied this question.

synapsesocial.com/papers/699bee1c1c6c6bad5397fde6https://doi.org/10.1253/circrep.cr-25-0345
Ask AI
Helpful
Bookmark
Share
View Full Paper