Research Advances in the Role of Lysosomes in Efferocytosis

Key Points

• To explore the multifaceted roles and molecular mechanisms of lysosomes in the process of efferocytosis.
• Systematic review of current literature on lysosome functions in efferocytosis.
• Analysis of lysosomal involvement in the stages of apoptotic cell clearance.
• Examination of lysosomes as central hubs for signal integration and metabolic regulation.
• Lysosomes play a key regulatory role in the initiation, execution, and effects of efferocytosis.
• Recent findings emphasize lysosomes' dynamic nature in response to apoptotic cells.
• Lysosomes are crucial for maintaining tissue homeostasis and inflammatory responses.