This systematic review evaluates the efficacy of platelet-rich plasma in otologic procedures, suggesting potential benefits for tympanic membrane repair.
Key Points
This review aims to assess the clinical outcomes associated with platelet-rich plasma in various otologic procedures.
Conducted a systematic review of studies from 2015 to 2025.
Included English-language human studies with clinical outcome data.
Searched across multiple databases including PubMed, EMBASE, and Cochrane Library.
Synthesized findings narratively due to methodological diversity.
PRP was associated with higher graft uptake (85.7% vs. 60%) and faster healing in tympanoplasty/myringoplasty.
Postoperative complications were low with no major safety concerns linked to PRP.
Limited evidence for SNHL indicates hearing improvement with intratympanic PRP compared to steroids.