February 24, 2026Expert Opinion on Biological Therapy0 citations
Biologic treatment patterns and challenges in defining difficult-to-treat disease in children with polyarticular juvenile idiopathic arthritis: a real-world study
The research aims to explore treatment patterns and the challenges in identifying difficult-to-treat disease in children with polyarticular juvenile idiopathic arthritis.
Analyzed real-world data from children suffering from polyarticular juvenile idiopathic arthritis.
Assessed associated markers like temporomandibular joint involvement and inflammatory markers.
Difficult-to-treat courses correlated with higher disease activity at the start of biologic treatment.
Elevated inflammatory markers were noted in patients classified as difficult-to-treat.
Temporomandibular joint involvement was linked to the challenges in treatment.
Abstract
D2T course was associated with temporomandibular joint involvement, elevated inflammatory markers, and higher disease activity at the initiation of the first biologic therapy.