What does this research mean for the field?

Iodixanol can induce acute kidney injury and subsequent multi-organ complications through alternative excretion mechanisms. Novelty: ClaimNovelty.NOVEL_FINDING. Consensus alignment: ConsensusAlignment.CHALLENGES_CONSENSUS.

What question did this study set out to answer?

The study aims to explore the mechanisms by which iodixanol induces acute kidney injury and associated multi-organ complications.

February 25, 2026International Journal of Clinical Pharmacology and Therapeutics1 citations

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Iodixanol-induced acute kidney injury and multi-organ complications via alternative excretion: A case report and mechanism exploration

LLLe Li LYLifang Yang HWHuifeng Wu

Key Points

The study aims to explore the mechanisms by which iodixanol induces acute kidney injury and associated multi-organ complications.
Case report analysis of iodixanol effects
Assessment of multi-organ injury
Evaluation of preoperative and postoperative management strategies
Iodixanol administration is linked to the risk of acute kidney injury
Multi-organ complications observed following iodixanol exposure
Effective preoperative assessment and postoperative monitoring are crucial to mitigate risks

Abstract

This case highlights the potential for iodixanol to induce VCME and subsequent multi-organ injury in the setting of AKI. Enhanced preoperative risk assessment, postoperative monitoring, and multidisciplinary management are essential for mitigating such rare but severe complications.

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Iodixanol-induced acute kidney injury and multi-organ complications via alternative excretion: A case report and mechanism exploration

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Abstract

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