PulseExploreJournal ClubDebatesTrendingResearchersJournals
Instagram
HomeExploreJournal ClubTrending
Synapse
⌘+K
Synapse
February 25, 2026Analytical Chemistry1 citations

Highly Sensitive Detection of ATP Using Aptamer-Functionalized Glass Nanopipette

Dual Recognition and Highly Sensitive Detection of ATP by Aptamer-Bridged MOF Functionalized Glass Nanopipette

View Full Paper
Ask AI
Bookmark
Share

Authors

YSYingci SongSLShuting LiLLL. Li

Discussion

Loading...

Member takes

Overview

Innovative nanopipette sensor enhances ATP detection sensitivity in biological samples, suggesting practical applications in biosensing.

Key Points

  • The aim is to improve ATP detection sensitivity through a dual-site recognition strategy using a nanopipette sensor.
  • Engineered a functionalized glass nanopipette with DNA-grafted ZIF-90.
  • Employed dual-site binding of ATP to enhance sensing efficiency.
  • Demonstrated linear response down to 0.1 nM ATP in cellular environments.
  • Achieved significant ionic current modulation through ATP-induced ZIF-90 collapse.
  • Compared to traditional methods, sensing performance was greatly enhanced with dual-site recognition.
  • Enabled direct probing of ATP concentration in cells without extensive signal amplification techniques.

Cite This Study

Song et al. (2026) studied this question.

synapsesocial.com/papers/699e911bf5123be5ed04e5e3https://doi.org/10.1021/acs.analchem.5c07972
View Full Paper
Ask AI
Bookmark
Share