Cerebellar infarction, an uncommon stroke subtype, presents unique diagnostic and therapeutic challenges due to its complex and varied clinical manifestations, as well as its potential for life-threatening complications. This review highlights the critical yet frequently overlooked nonmotor symptoms of cerebellar infarction, encompassing cognitive, emotional, and psychiatric domains, which substantially impact patient’s outcomes, moving beyond the traditional focus on motor syndromes. In addition, we emphasize emerging therapeutic innovations such as repetitive transcranial magnetic stimulation and deep brain stimulation (DBS), which represent promising avenues for intervention. Advances in neuroimaging and molecular biomarkers are also discussed, as they have refined diagnostic precision, deepened the understanding of pathogenic mechanisms, and facilitated early recognition alongside personalized treatment strategies. Simultaneously, the identification of risk factors and pathogenic events associated with cerebellar infarction is of importance in preventing this disease. Several new drugs, new endovascular and surgical therapies, and comprehensive rehabilitation therapies may significantly improve the prognosis of this devastating disease. This review provides a contemporary overview of advances in the clinical understanding, imaging, and management of cerebellar infarction, highlighting the implementation of effective interventions from acute treatment to long-term recovery.
Liu et al. (Mon,) studied this question.