Preclinical study shows decellularized corneal lenticules can effectively close macular holes, suggesting potential therapeutic applications.
Our preliminary results suggest that decellularized hCLs can be successfully implanted to close FTMHs in our preclinical ex vivo model of study, paving the way for future research into bioengineered hCLs for therapeutic purposes. Video available for this article. Video 1: OCT video recordings during the setup of the ex vivo FTMH model with hCL implantation (MP4 157096 kb).
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Ruggeri et al. (2026) studied this question.
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