Comorbid insomnia and obstructive sleep apnea increase risks of cardiovascular and cerebrovascular diseases | Synapse
February 26, 2026
Comorbid insomnia and obstructive sleep apnea increase risks of cardiovascular and cerebrovascular diseases
Key Points
Examine the risks associated with comorbid insomnia and obstructive sleep apnea (COMISA) on cardiovascular diseases.
Analyzed long-term outcomes for patients with COMISA
Evaluated risks of cardiovascular and cerebrovascular diseases
Focused on thrombotic event occurrences
COMISA significantly raises the risk of cardiovascular diseases
Particularly elevated risks for cerebrovascular diseases and thrombotic events
Identified COMISA as a high-risk clinical phenotype for CCVD
Abstract
COMISA was associated with higher long-term risks of several CCVD subtypes, particularly cerebrovascular and thrombotic events, further characterizing COMISA as a high-risk clinical phenotype.