Case report reveals diagnostic challenges of MEN-1 in a young male, indicating a need for multidisciplinary care and psychosocial support.
This case report describes a 32-year-old Pakistani male who was initially admitted to a tertiary care hospital with Typhoid fever, but later developed recurrent life-threatening hypoglycemia. Extensive investigations revealed elevated insulin and C-peptide levels, a pituitary microadenoma, and a somatostatin-avid gastric lesion, leading to the diagnosis of Multiple Endocrine Neoplasia type 1 (MEN-1). Management included dextrose infusions, somatostatin-analogue therapy, and supportive care. The case highlights the diagnostic challenges of MEN-1 in atypical presentations and resource-limited settings, underscoring the need for a multidisciplinary approach to treatment and psychosocial support.
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Rehman et al. (2025) studied this question.
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