Longitudinal study reveals prognostic value of new grading system for visual function in choroideremia carriers, suggesting improved clinical monitoring.
We proposed a novel fundus grading system for choroideremia carriers and demonstrated its strong clinical utility and prognostic value. The granular type confers a favorable prognosis, whereas the other three types exhibit progressive deterioration. Baseline phenotypic grading is the best indicator of long-term outcomes, underscoring its value in clinical monitoring and therapeutic trial design.
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Han et al. (2026) studied this question.
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