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Synapse
February 26, 2026

Therapeutic Role and Immunogenic Characteristics of Cancer Testis Antigens in Breast Cancer: A Review.

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Authors

MSMotahareh Sheikh-HosseiniMNMostafa NeissiMMMohammad Moarefzadeh

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Overview

Narrative review explores the role of cancer testis antigens in breast cancer, suggesting implications for immunotherapy and improving clinical outcomes.

Key Points

  • This review aims to assess the therapeutic roles and immunogenic features of cancer testis antigens in breast cancer.
  • Identified 255 articles from multiple databases including PubMed and Scopus.
  • Selected 30 articles for detailed evaluation and discussion in the review.
  • Focused on cancer testis antigens and their potential applications in immunotherapy and diagnosis.
  • Identified cancer testis antigens as promising therapeutic targets in breast cancer.
  • Highlighted the unique immunogenic characteristics of cancer testis antigens.
  • Outlined challenges such as antigen heterogeneity and immune evasion affecting treatment outcomes.

Cite This Study

Sheikh-Hosseini et al. (2026) studied this question.

synapsesocial.com/papers/699f95951bc9fecf3dab3896https://doi.org/10.22074/cellj.2026.2044248.1703
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