What question did this study set out to answer?

To investigate the relationship between serum pyridoxal 5'-phosphate and kidney stone risk, considering inflammation's mediating effect.

February 26, 2026European journal of medical research0 citationsOpen Access

Association between serum pyridoxal 5'-phosphate and kidney stone risk: neutrophil count as a partial mediator

DCDi ChenAnhui University WFWenju FanThe Second Nanning People's Hospital QZQiufeng Zhou81th Hospital of PLA

Key Points

To investigate the relationship between serum pyridoxal 5'-phosphate and kidney stone risk, considering inflammation's mediating effect.
Focused on participants with BMI between 25-29.9.
Excluded individuals with diabetes and hypertension.
Analyzed the correlation between serum PLP levels and kidney stone risk.
Higher serum PLP levels corresponded with reduced kidney stone risk.
Inflammation indicators, like neutrophil count, partially mediated this association.

Abstract

Among participants with a BMI of 25-29.9, without diabetes or hypertension, higher serum PLP levels were associated with a lower KS risk. Inflammation may affect the association between PLP and KS risk.

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