Effect of prophylactic platelet transfusion on bleeding risk in patients with cirrhosis and thrombocytopenia undergoing ultrasound-guided liver biopsy

December 11, 2025ULTRASONOGRAPHYOpen Access

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Key Points

The aim is to evaluate the effect of prophylactic platelet transfusion on bleeding risk during liver biopsy in patients with cirrhosis and thrombocytopenia.
Conducted a prospective analysis of patients undergoing ultrasound-guided liver biopsy.
Assessed baseline platelet counts and defined thrombocytopenia levels.
Implemented prophylactic platelet transfusions prior to the biopsy for selected patients.
Monitored bleeding complications post-biopsy for comparison.
Prophylactic platelet transfusion significantly reduced bleeding complications.
Patients without transfusion experienced higher bleeding rates compared to those who received transfusions.
Overall safety profiles and outcomes were comparable across patient groups.

Investigates how platelet transfusion affects bleeding risk in patients with liver disease undergoing biopsy, suggesting potential benefits.

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Jang et al. (2025) studied this question.

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