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February 27, 2026JACC Case Reports0 citationsOpen Access

Swallowing Syncope With Atrial Fibrillation Treated by Wide Area Circumferential Ablation and Cardioneuroablation

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KCKit Hou ChiangSarawak Biodiversity CentreKKKenneth Kay Leong KhooSarawak Biodiversity CentreLLL.K. LeongSarawak Biodiversity Centre

Key Result

Combined wide area circumferential ablation (WACA) and cardioneuroablation (CNA) provide lasting relief of vagally mediated swallowing syncope in AF patients.

Key Points

  • The study aims to evaluate the effectiveness of combined wide area circumferential ablation and cardioneuroablation in treating swallowing syncope associated with atrial fibrillation.
  • Combination of wide area circumferential ablation and cardioneuroablation performed on patients.
  • Focus on individuals experiencing swallowing syncope due to atrial fibrillation.
  • Assessment of relief duration and symptom recurrence.
  • Patients experienced durable relief from swallowing syncope.
  • Significant reduction in vagally mediated episodes was reported.

Structured PICO

Does combined WACA and CNA provide relief of vagally mediated swallowing syncope in patients with AF?

P
Population
Patients with atrial fibrillation (AF) and vagally mediated swallowing syncope
I
Intervention
Combined Wide Area Circumferential Ablation (WACA) and Cardioneuroablation (CNA)
O
Outcome
Relief of vagally mediated swallowing syncope

Combined WACA and CNA provides durable relief of vagally mediated swallowing syncope in patients with atrial fibrillation.

Abstract

Combined WACA and CNA provide durable relief of vagally mediated swallowing syncope in patients with AF.

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Cite This Study

Chiang et al. (2026) studied this question. Combined wide area circumferential ablation (WACA) and cardioneuroablation (CNA) provide lasting relief of vagally mediated swallowing syncope in AF patients.

synapsesocial.com/papers/69a1344fed1d949a99abe1a2https://doi.org/10.1016/j.jaccas.2026.107042
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Long-Term Evaluation of the Vagal Denervation by Cardioneuroablation Using Holter and Heart Rate Variability2020 · 108 citations
  2. 2Autonomic Denervation Added to Pulmonary Vein Isolation for Paroxysmal Atrial Fibrillation2013 · 424 citations
  3. 3Efferent Vagal Innervation of the Canine Atria and Sinus and Atrioventricular Nodes1997 · 350 citations
  4. 4Neurally Mediated Syncopal Syndromes: Pathophysiological Concepts and Clinical Evaluation1997 · 117 citations
  5. 5Autonomic Effects of Pulsed Field vs Thermal Ablation for Treating Atrial Fibrillation2024 · 41 citations