Experimental findings indicate that exosomal EPH A2 enhances metastatic potential in breast cancer, suggesting a new therapeutic target.
The results underscore the pivotal function of exosomal EPHA2 in mediating the transfer of metastatic potential among heterogeneous breast cancer cell populations. Targeting the EPHA2-TGF-βRI signaling axis may provide a novel therapeutic approach for preventing or limiting breast cancer metastasis.
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Liu et al. (2026) studied this question.
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