Systematic review reveals no significant post-endodontic pain differences in various sodium hypochlorite concentrations, suggesting lower concentrations may be safer.
Within the limitations of the present study, no significant differences in post-endodontic pain were found between high and low NaOCl concentrations. However, concentrations < 5% might be associated with less pain incidence. Further well-designed clinical trials with standardized methodologies are needed to provide more conclusive evidence.
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Teja et al. (2026) studied this question.
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