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February 27, 2026International Journal of Preventive MedicineOpen Access

Which One Can Detect More Osteopenia and Osteoporosis in Rheumatoid Arthritis Patient? Dual-Energy X-Ray Absorptiometry (DXA) or Trabecular Bone Score (TBS)

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Authors

DMDiba MonjeziBSBehrokh ShojaieMSMansour Salesi

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Overview

This retrospective study evaluates DXA and TBS for diagnosing osteopenia and osteoporosis in rheumatoid arthritis, suggesting the superiority of DXA.

Key Points

  • This study aims to compare the diagnostic efficacy of dual-energy X-ray absorptiometry (DXA) and trabecular bone score (TBS) for detecting osteopenia and osteoporosis in rheumatoid arthritis patients.
  • Retrospective analysis of DXA and TBS data from 88 rheumatoid arthritis patients and 52 healthy controls.
  • Descriptive and inferential statistics were employed to evaluate diagnostic performance.
  • Comparison of percentages of diagnosed osteopenia and osteoporosis between DXA and TBS.
  • DXA detected 51.14% of RA patients with osteopenia, compared to 31.82% by TBS.
  • For osteoporosis, DXA diagnosed 26.14%, while TBS detected only 21.59%.
  • TBS showed lower diagnostic percentages for both conditions, indicating potential lower accuracy compared to DXA.

Cite This Study

Monjezi et al. (2026) studied this question.

synapsesocial.com/papers/69a135b0ed1d949a99abfd24https://doi.org/10.4103/ijpvm.ijpvm_218_23
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Also Consider

Synapse has enriched 5 closely related papers on similar clinical questions. Consider them for comparative context:

  1. 1Contribution of Trabecular Bone Score to Fracture Risk Stratification Beyond Bone Mineral Density in Women with Rheumatoid Arthritis: Results from a Cross-Sectional Cohort2026
  2. 2Bone microarchitecture and fracture risk in rheumatoid arthritis2024 · 1 citations
  3. 3Risk of Osteoporosis and Degraded Trabecular Bone Score in Rheumatoid Arthritis Patients2025
  4. 4Clinical integration of trabecular bone score in precision osteoporosis care: a position statement by the Egyptian academy of bone and muscle health2026
  5. 5Bone mineral density, trabecular bone score, and uric acid in patients with rheumatoid arthritis2025