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February 28, 2026CureusOpen Access

Preoperative Indicators of Graft Rejection in Patients With Heart Transplantation: A Single-Center Retrospective Study

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Authors

LHLaurentiu HumaHSHoratiu SuciuDMDiana Andreea Moldovan

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Overview

Single-center retrospective study assesses preoperative factors predicting graft rejection in heart transplant recipients, indicating potential interventions.

Key Points

  • The study aims to identify preoperative factors related to graft rejection in heart transplant patients with different cardiomyopathy etiologies.
  • Collected data from patients who underwent cardiac transplant between 2011 and 2023.
  • Initial cohort of 51 patients, with 44 patients analyzed after excluding those with incomplete data.
  • Compared means and medians between ischemic and nonischemic groups.
  • Investigated associations with hospitalization parameters and clinical outcomes.
  • Ischemic group showed higher mean age, weight, body mass index, and body surface area.
  • Nonischemic group was linked to the Quilty effect and graft rejection.
  • Expression of human leukocyte antigen-A variant correlated with graft rejection and Quilty effect.

Cite This Study

Huma et al. (2026) studied this question.

synapsesocial.com/papers/69a285da0a974eb0d3c00d61https://doi.org/10.7759/cureus.c407
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