A case report reveals the rare occurrence of ascending necrotizing mediastinitis from intra-abdominal sources, indicating critical implications for diagnosis.
INTRODUCTION: Necrotizing fasciitis (NF) is a rapidly progressing soft-tissue infection associated with high mortality. While descending necrotizing mediastinitis (DNM) from cervical infections is well characterized, ascending necrotizing mediastinitis (ANM) originating from intra-abdominal sources is extremely rare.
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Lee et al. (2026) studied this question.
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